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Percheron Therapeutics
ASX: PERUS OTC: PERCF

Providing hope to patients with cancer

Harnessing cutting edge science to improve patients lives

Percheron Therapeutics is a clinical-stage biotechnology company advancing first-in-class immuno-oncology therapies to tackle some of the most difficult-to-treat cancers.

Dr Michael Baker, MD and CEO of Percheron Therapeutics
Dr Michael BakerMD & CEOPercheron Therapeutics

A welcome from our MD & CEO

Your dedicated resource for staying informed and engaged with our journey.

As we advance our lead asset, HMBD-002, for the treatment of various cancers, we are committed to keeping investors updated with the latest trial milestones, market insights, and corporate progress.

Visit our website for easy access to key announcements, reports, and to learn about opportunities to connect with our team.

We value your support and look forward to sharing our growth and success with you.

Thank you for being part of Percheron Therapeutics’ Journey.

How HMBD-002 works

Immuno-Oncology

One of the key advances in cancer over recent decades has been the understanding of how a growing tumour interacts with the body’s immune system.

  • T cell
  • Suppressed T cell
  • Tumour cells
  • MDSC (myeloid-derived suppressor cell)
  • TAM (tumour-associated macrophage)
  • VISTA
  • HMBD-002 (VISTA antibody)
Step 1 of 5

Ordinarily, our immune system protects us against pre-cancerous cells, in much the same way that it protects against infection.

Monoclonal Antibodies

HMBD-002 is a member of class of drugs known as monoclonal antibodies. Like the antibodies that are produced by our own immune system, monoclonal antibodies allow very specific targeting of pathological cells. Instead of targeting bacteria, for example, monoclonal antibodies can be designed to target cancer cells or, in the case of HMBD-002, to target the signaling between cancer cells and immune cells.

  • VISTA
  • Light chains
  • Stem

Development of HMBD-002

HMBD-002 is well-advanced in clinical development.

HMBD-002 was discovered by Hummingbird Bioscience, one of the world’s most innovative companies in the field of monoclonal antibody drug development.

HMBD-002 has shown activity in a wide range of animal models of cancer, and has shown evidence of synergy when combined with other immuno-oncology drugs such as Keytruda® (pembrolizumab).

48A phase I study in 48 patients was conducted at leading centres in the United States. It showed HMBD-002 to be very safe and well-tolerated, and provided valuable information about the pharmacology of the drug to inform future studies.

Our commitment

At Percheron our commitment goes beyond the science of novel therapies, and we are determined to engage constructively with patients and advocacy organisations.

Compassionate Use and Expanded Access Policy
Three generations of a family smiling together

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Price-sensitive announcements (hidden source for the ticker and hero card)

Quarterly Activities Report and Appendix 4C

Quarterly Activities Report and Appendix 4C

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Percheron raises $2.3m to fully fund clinical trial in AML

Percheron raises $2.3m to fully fund clinical trial in AML

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Vanderbilt Health to conduct clinical trial of HMBD-002

Vanderbilt Health to conduct clinical trial of HMBD-002

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Appendix 4E and Annual Report

Appendix 4E and Annual Report

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