Announcement PDF Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 1 / 7 Announcement Summary Entity name PERCHERON THERAPEUTICS LIMITED Announcement Type New announcement Date of this announcement Friday November 06, 2026 The +securities to be quoted are: Please refer to the response to Q2.3d for further information about the type of securities to be quoted and the circumstances of the issue. 280,000,000 securities were previously announced using an Appendix 3B on 1 September 2026. The relevant documents will not link to this form. 294,987,505 securities were issued and announced as unquoted securities during 2026. Total number of +securities to be quoted ASX +security code Security description Number of +securities to be quoted Issue date New class - code to be confirmed Options exercisable at $0.01 on or before 15 April 2028 574,987,505 06/11/2026 Refer to next page for full details of the announcement Other Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 2 / 7 Part 1 - Entity and announcement details 1.1 Name of entity PERCHERON THERAPEUTICS LIMITED We (the entity named above) apply for +quotation of the following +securities and agree to the matters set out in Appendix 2A of the ASX Listing Rules. 1.2 Registered number type ABN Registration number 41095060745 1.3 ASX issuer code PER 1.4 The announcement is 1.5 Date of this announcement 6/11/2026 New announcement Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 3 / 7 Part 2 - Type of Issue 2.1 The +securities to be quoted are: Please refer to the response to Q2.3d for further information about the type of securities to be quoted and the circumstances of the issue. 2.2 The +class of +securities to be quoted is: 2.3c Have these +securities been offered under a +disclosure document or +PDS? 2.3c.1 Date of +disclosure document or +PDS? 4/11/2026 2.3d Please provide any further information needed to understand the circumstances in which you are applying to have these +securities quoted on ASX, including why the issue of the +securities has not been previously announced to the market in an Appendix 3B 280,000,000 securities were previously announced using an Appendix 3B on 1 September 2026. The relevant documents will not link to this form. 294,987,505 securities were issued and announced as unquoted securities during 2026. Yes New +securities in a class that is not yet quoted on ASX ("new class") Other Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 4 / 7 Part 3C - number and type of +securities to be quoted (new class) where issue has not previously been notified to ASX in an Appendix 3B New +securities ASX +security code New class - code to be confirmed +Security description Options exercisable at $0.01 on or before 15 April 2028 +Security type Options ISIN code Issue date 6/11/2026 Will all the +securities issued in this class rank equally in all respects from the issue date? Have you received confirmation from ASX that the terms of the +securities are appropriate and equitable under listing rule 6.1? Distribution Schedule Provide a distribution schedule for the new +securities according to the categories set out in the left hand column - including the number of recipients and the total percentage of the new +securities held by the recipients in each category. Number of +securities held Number of holders Total percentage of +securities held For example, to enter a value of 50% please input as 50.00 1 - 1,000 22 0.00 % 1,001 - 5,000 62 0.03 % 5,001 - 10,000 28 0.04 % 10,001 - 100,000 172 1.29 % 100,001 and over 186 98.64 % Options Details +Security currency AUD - Australian Dollar Exercise price AUD 0.01000000 Expiry date 15/4/2028 No Yes Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 5 / 7 Details of the type of +security that will be issued if an option is exercised PER : ORDINARY FULLY PAID Number of +securities that will be issued if an option is exercised one fully paid ordinary share in Percheron Therapeutics Limited. Please provide a URL link for a document lodged with ASX setting out the material terms of the +securities to be quoted or provide the information by separate announcement. Option terms were provided in the prospectus lodged on 6 November 2026 https://asx.api.cmfyapp.com/asx-research/1.0/ file/2924-03157710-3A705749&v=undefined Issue details Number of +securities to be quoted 574,987,505 Are the +securities being issued for a cash consideration? Please describe the consideration being provided for the +securities Free attaching options issued during rights issue (April 2026) and placement (Sept and Oct 2026). Please provide an estimate (in AUD) of the value of the consideration being provided per +security for the +securities to be quoted 0.000000 Any other information the entity wishes to provide about the +securities to be quoted The purpose(s) for which the entity is issuing the securities Other Please provide additional details Free attaching options issued during rights issue (April 2026) and placement (Sept and Oct 2026). No Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 6 / 7 Part 4 - Issued capital following quotation Following the quotation of the +securities the subject of this application, the issued capital of the entity will comprise: The figures in parts 4.1 and 4.2 below are automatically generated and may not reflect the entity's current issued capital if other Appendix 2A, Appendix 3G or Appendix 3H forms are currently with ASX for processing. 4.1 Quoted +securities (total number of each +class of +securities quoted on ASX following the +quotation of the +securities subject of this application) ASX +security code and description Total number of +securities on issue PER : ORDINARY FULLY PAID 1,982,415,536 New class - code to be confirmed : Options exercisable at $0.01 on or before 15 April 2028 574,987,505 4.2 Unquoted +securities (total number of each +class of +securities issued but not quoted on ASX) ASX +security code and description Total number of +securities on issue PERAO : OPTION EXPIRING 20-MAY-2028 EX $0.035 107,053,966 PERAR : PERFORMANCE RESTRICTED STOCK UNITS 75,000,000 PERAI : OPTION EXPIRING 07-AUG-2028 EX $0.07 5,017,500 PERAQ : OPTION EXPIRING 15-APR-2028 EX $0.01 294,987,505 PERAJ : OPTION EXPIRING 30-JUN-2028 EX $0.061 3,000,000 PERAL : OPTION EXPIRING 29-NOV-2029 EX $0.26 4,036,487 PERAN : OPTION EXPIRING 29-NOV-2029 EX $0.52 4,036,486 PERAM : OPTION EXPIRING 29-NOV-2029 EX $0.39 4,036,487 PERAB : OPTION EXPIRING 03-JUL-2031 EX $0.004 8,100,000 PERAK : OPTION EXPIRING 04-JUL-2029 EX $0.083 9,000,000 Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 7 / 7 Part 5 - Other Listing Rule requirements 5.1 Are the +securities being issued under an exception in Listing Rule 7.2 and therefore the issue does not need any security holder approval under Listing Rule 7.1? 5.2 Has the entity obtained, or is it obtaining, +security holder approval for the issue under listing rule 7.1? 5.2a Date of meeting or proposed meeting to approve the issue under listing rule 7.1 7/10/2026 Yes No