Announcement PDF TOP 20 AND DISTRIBUTION LIST FOR OPTION HOLDERS Melbourne, Australia – 6 November 2026: Percheron Therapeutics Limited (ASX: PER) ('the Company'), an international biotechnology company focused on developing novel therapies for oncology, is pleased to provide the Top 20 Option Holders and Distribution List of Option Holders in relation to the issue of New Options and the quotation of the PERAQ options as previously announced 1 September 2026 and 30 October 2026. ~ ENDS ~ About Percheron Therapeutics Limited Percheron Therapeutics Limited [ASX: PER | US OTC: PERCF] is a publicly listed biotechnology company focused on the development and commercialisation of novel therapies for oncology. The company’s lead program is HMBD-002, a monoclonal antibody targeting the immune checkpoint regulator, VISTA. HMBD-002 has completed a phase 1 clinical trial in patients with advanced cancer, showing the drug is generally safe and well tolerated, and Percheron aims to commence further clinical trials in CY2026. For more information, please contact info@PercheronTx.com. This announcement has been authorised for release to the Australian Securities Exchange by the Percheron Board of Directors Top Holders Report at at 6 - 11- 2026 Percheron Therapeutics Limited Securities class - Listed Opt Exp 15 April 2028 @ $0.01 Name/Address 1 Name/Address 2 Name/Address 3 Options $0.01 Expiring 15 April 2028 % IC L39 Pty Ltd <No 12 A/C> 77,500,000 13% Mr Richard John Mann 30,779,461 5% Kea Holdings Pty Ltd <10S Holding A/C> 25,000,000 4% 1215 Capital Pty Ltd 25,000,000 4% Deck Chair Holdings Pty Ltd 25,000,000 4% HSBC Custody Nominees (Australia) Limited 15,600,000 3% Kea Holdings Pty Ltd <Ios Holding A/C> 15,000,000 3% Deck Chair Holdings Pty Ltd 15,000,000 3% Deck Chair Holdings Pty Ltd 15,000,000 3% Non Correlated Capital Pty Ltd <Investius PB Micro Cap A/C> 14,000,000 2% Kea Holdings Pty Ltd <Ios Holding A/C> 13,395,238 2% Mann Beef Pty Ltd 11,220,539 2% Dr James Stuart Garner 10,700,000 2% Dmmy Holdings Pty Ltd <Dmmy Investment A/C> 10,000,000 2% Riya Investments Pty Ltd 9,250,000 2% Allekian Exchange Pty Ltd 9,250,000 2% Alcanterra Group Pty Ltd 8,000,000 1% Major Holdings Pty Ltd 8,000,000 1% Mutual Investments Pty Ltd <Mitchell Family A/C> 7,078,796 1% Mrs Carolyn A Bernardi & Mr Pierre Ralph Bernardi <Carolyn Bernardi Super F A/C> 6,000,000 1% Top 20 Holders 350,774,034 61% Total on Issue 574,897,505 100% Percheron Therapeutics Limited Analysis of Holdings as at 06-11-2026 Securities Options $0.01 Expiring 15 April 2028 Holdings Ranges Holders Total Units % 1-1,000 22 10,326 0.002 1,001-5,000 62 182,649 0.032 5,001-10,000 28 232,630 0.040 10,001-100,000 172 7,397,979 1.287 100,001-999,999,999 186 567,163,921 98.639 Totals 470 574,987,505 100.000